Beilstein J. Org. Chem.2016,12, 2005–2011, doi:10.3762/bjoc.12.187
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Keywords: Cacchiannulation; cross-coupling; heterocycles; Sonogashira; sustainable solvent; Introduction
The Sonogashira reaction [1][2] (Scheme 1) is a robust and broadly applicable Pd-catalysed bond-forming process that, alongside the Suzuki–Miyaura reaction [3], has steadily become an indispensible